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Resistin

CAT: 0209-101-M618Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M618Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family; Resistin, RELM-α and RELM-β share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis.
Synonyms
RETN; ADSF; RSTN; XCP1; FIZZ3; RETN1
NCBI Gene ID
56729
UniProt
Q9HD89
Accession Number
NP_065148
Accession Number mRNA
NM_020415
Chromosomal Location
19p13.2
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human Resistin
Clone
(#9F28)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2

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