RANTES (CCL 5) Recombinant Protein

RANTES (CCL 5) Recombinant Protein

• Description: RANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant human RANTES is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
• Synonyms: CCL5; SISd; SCYA5; RANTES; TCP228; D17S136E
• CAS Number: 9000-83-3
• NCBI Gene ID: 6352
• UniProt: P13501
• Accession Number: NP_002976.2
• Accession Number mRNA: NM_002985
• Gene Location: 17q11.2-q12
• Host: E. coli
• Origin Species: Human
• Species Reactivity: Cow, Hamster, Monkey, Mouse, Rat, Human, Leech, Bacteria
• Sequence: SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS
• Detection Range: Determined by its ability to chemoattract human blood monocytes using a concentration range of 1.0-10.0 ng/ml.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 98% by SDS-PAGE & HPLC analyses
• Length: 68
• Form: Lyophilized
• Molecular Weight: 7.8 kDa
• Shipping Conditions: Room Temperature