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Omgp

CAT: 0209-103-M445Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-103-M445Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Oligodendrocyte myelin glycoprotein (OMgp) is a GPI-linked glycoprotein that exhibits multiple leucine-rich repeats and putative N- and O-linked glycosylation sites. It is primarily expressed on the surfaces of oligodendrocytes and large projection neurons, including Purkinje and pyramidal cells. OMgp binds a heterodimeric receptor complex consisting of Nogo R and NGF R/TNFRSF16 to collapse axonal growth cones and inhibit axonal and neurite outgrowth.
Synonyms
OMG; OMGP
NCBI Gene ID
4974
UniProt
Q63912
Accession Number
NP_062282.2
Accession Number mRNA
NM_019409.2
Chromosomal Location
17q11.2
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Recombinant mouse Omgp
Clone
(#5H73)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2