NrCAM

• Description:

  NgCAM related cell adhesion molecule (or NrCAM), also known as Bravo, belongs to the L1 family of cell adhesion molecules, which includes L1, neurofascin and close homolog of L1 (CHL-1/L1CAM-2) . These molecules are type I transmembrane proteins that have six Ig-like domains and 4 to 5 Fibronectin type III-like domains in their extracellular region. They also share a conserved cytoplasmic region containing an ankyrin-binding site. L1 family cell adhesion molecules are expressed primarily in the nervous system where they share overlapping functions in controlling axonal growth and guidance.

• Synonyms:

  NRCAM

• NCBI Gene ID:

  4897

• UniProt:

  Q92823

• Accession Number:

  NP_005001.3

• Accession Number mRNA:

  NM_005010.4

• Chromosomal Location:

  7q31

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Recombinant human NrCAM

• Clone:

  (#8E25)

• Applications:

  WB

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Mouse

• Isotype:

  IgG2