MIP-3 (CCL23) Recombinant Protein

MIP-3 (CCL23) Recombinant Protein

• Description: MIP-3 is a CC chemokine that signals through the CCR1 receptor. MIP-3 chemoattracts monocytes, resting T-lymphocytes and neutrophils, but does not chemoattract activated lymphocytes. Additionally, MIP-3 has been shown to inhibit colony formation of bone marrow myeloid immature progenitors. Recombinant human MIP-3 is an 11.3 kDa protein containing 99 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
• Synonyms: CCL23; CKb8; MIP3; Ckb-8; MIP-3; MPIF-1; SCYA23; Ckb-8-1; CK-BETA-8
• CAS Number: 9000-83-3
• NCBI Gene ID: 6368
• UniProt: P55773
• Accession Number: NP_005055
• Accession Number mRNA: NM_005064
• Gene Location: 17q12
• Host: E. coli
• Origin Species: Human
• Species Reactivity: Human, Mouse
• Sequence: RVT kDaETEF MMSKLPLENP VLLDRFHATS ADCCISYTPR SIPCSLLESY FETNSECSKP GVIFLTKKGR RFCANPSDKQ VQVCMRMLKL DTRIKTRKN
• Detection Range: Determined by its ability to chemoattract human T cell population using a concentration of 10-50 ng/ml.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 98% by SDS-PAGE & HPLC analyses
• Length: 99
• Form: Lyophilized
• Molecular Weight: 11 kDa
• Shipping Conditions: Room Temperature