MIP-2 (CXCL2, Gro-beta) Recombinant Protein

• Description:

  All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant mouse MIP-2 is a 7.8 kDa protein consisting of 73 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.

• Synonyms:

  Cxcl2; GROb; Gro2; Mip2; Scyb; MIP-2; Scyb2; MIP-2a; Mgsa-b; CINC-2a

• CAS Number:

  9000-83-3

• NCBI Gene ID:

  20310

• UniProt:

  P10889

• Accession Number:

  NP_033166.1

• Accession Number mRNA:

  NM_009140.2

• Gene Location:

  5 E1; 5 51.0 cM

• Host:

  E. coli

• Origin Species:

  Mouse

• Species Reactivity:

  Human, Mouse

• Sequence:

  AVVASELRCQ CLKTLPRVDF KNIQSLSVTP PGPHCAQTEV IATLKGGQKV CLDPEAPLVQ KIIQKILNKG KAN

• Detection Range:

  Determined by its ability to chemoattract total human neutrophils using a concentration range of 1.0-10.0 ng/ml.

• Endotoxin:

  < 0.1 ng/µg of protein (<1EU/µg)

• Purity:

  > 98% by SDS-PAGE & HPLC analyses

• Length:

  73

• Form:

  Lyophilized

• Molecular Weight:

  7.8 kDa

• Shipping Conditions:

  Room Temperature