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Megalin

CAT: 0209-101-M144Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M144Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Megalin/gp330, an approx. 600 kDa transmembrane glycoprotein is a large cell surface receptor that mediates the binding and internalization of a number of structurally and functionally distinct ligands from the lipoprotein and protease:protease inhibitor families.
Synonyms
LRP2; DBS; GP330; low density lipoprotein receptor-related protein 2; Glycoprotein 330
NCBI Gene ID
4036
UniProt
P98164
Accession Number
NP_004516.2
Accession Number mRNA
NM_004525.2
Reactivity
Anti-Human
Cross Reactivity
Human, rat, mouse
Target Antigen
Purified human Megalin
Clone
(#CD7D5)
Applications
IHC; IF
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Bioactivity
IF/ IHC: Use at 2-5 µg/ml
Form
Lyophilized
Buffer
PBS
Reconstitution
Water
Molecular Weight
600 kDa
Storage Conditions
The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
Notes
The antibody cross-reacts with rat and mouse Megalin.
Host or Source
Mouse
Isotype
IgG1

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