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Marapsin

CAT: 0209-103-M433Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-103-M433Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Marapsin, Pancreasin, and channel-activating protease 2 (CAP2), encoded by the Prss27 gene, are different names given for the same serine protease that is expressed strongly in the pancreas. The mouse protein is synthesized with a signal peptide (amino acid residues 1-22), a pro peptide (residues 23-37) and amature chain (residues 38-290) corresponding to the serine protease domain. The fulllengthprotein was expressed and the secreted protein purified. The N-terminalsequencing results indicate that the purified protein is a disulfide bond-linked dimer formed between the pro peptide and the mature chain. The active enzyme has lowactivity against peptide substrates tested, but high activity against thioester substrates. The peptidase activity is inhibited by 20 mM benzamidine.
Synonyms
Prss27; Mpn; CAPH2; marapsin
NCBI Gene ID
213171
UniProt
Q8BJR6
Accession Number
NP_780649.1
Accession Number mRNA
NM_175440.4
Chromosomal Location
17 A3.3; 17 10.6 cM
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Mouse recombinant protein of Marapsin
Clone
(#9D66)
Applications
WB
Purification Method
Protein A/G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2