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LIF

CAT: 0209-102-PA05SSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-102-PA05SSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Leukemia Inhibitory Factor also called LIF is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78% identity in its amino acid sequence. Human LIF is as active on human cells as is it is on mouse cells, though mouse LIF is about 1000 fold less active on human cells, than human LIF.
Synonyms
LIF; CDF; DIA; HILDA; MLPLI
NCBI Gene ID
3976
UniProt
P15018
Accession Number
NP_002300.1
Accession Number mRNA
NM_002309.4
Chromosomal Location
22q12.2
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human LIF (RT #200-008)
Clone
Rabbit IgG
Applications
WB
Purification Method
Protein-A purified
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Bioactivity
Western Blot: Use 2-5 µg/ml
Form
Lyophilized
Buffer
PBS
Reconstitution
Water
Storage Conditions
The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
Host or Source
Rabbit

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