Leptin

• Description :

  Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in various in vivo models. Recombinant Rat Leptin is a 16.2 kDa protein containing 147 amino acid residues.

• Synonyms :

  Lep; ob; obese

• NCBI Gene ID :

  25608

• UniProt :

  P50596

• Accession Number :

  NP_037208

• Accession Number mRNA :

  NM_013076

• Chromosomal Location :

  4q22

• Reactivity :

  Anti-Rat

• Cross Reactivity :

  Rat

• Target Antigen :

  Recombinant Rat Leptin

• Clone :

  Goat IgG

• Applications :

  ELISA, WB

• Purification Method :

  Antigen-affinity purified

• Assay Protocol :

  Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

• Form :

  Lyophilized from PBS

• Buffer :

  PBS

• Reconstitution :

  Water

• Storage Conditions :

  The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.

• Host or Source :

  Goat