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LAMP

CAT: 0209-101-M545Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M545Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The LAMP (lysosomal associated membrane protein) family consists of two members, LAMP-1 and LAMP-2. They are ubiquitously expressed type I transmembrane glycoproteins found in lysosomal and cell membranes. They are only 37% amino acid identical, and show no definitive structural domains. They are involved in autophagy and may bind selectins on the cell surface.
Synonyms
LAMP1; LAMPA; CD107a; LGP120
NCBI Gene ID
3916
UniProt
P11279
Accession Number
NP_005555.2
Accession Number mRNA
NM_005561
Chromosomal Location
13q34
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human LAMP
Clone
(#3H44)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

UniProtKB · P11279

Lysosome-associated membrane glycoprotein 1

LAMP1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P11279
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LAMP1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
LAMP-1, Lysosome-associated membrane protein 1
EC number
—
Processing
Precursor
Secondary accessions
B4DWL3, Q8WU33, Q96I40, Q9BRD2, Q9NP13
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneEndosomeLysosomeMembrane

PTM

Disulfide bondGlycoprotein

Molecular function

Host cell receptor for virus entryReceptor

Biological process

Host-virus interaction

Domain

SignalTransmembraneTransmembrane helix

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