Lactogen, placental

• Description:

  Bovine recombinant placental lactogen, one polypeptide chain containing 164 amino and an additional Ala at N-terminus acids and having a molecular mass of ~ 23 kDa, was purified by proprietary chromatographic techniques . Bovine recombinant placental lactogen is also capable of activating human and other heterologous growth hormone receptors but not ruminant GH receptors.

• Synonyms:

  Chorionic somatomammotropin hormone 1, BPLP-I, Placental lactogen I

• NCBI Gene ID:

  281097

• UniProt:

  P09611

• Accession Number:

  AAA30739.1

• Accession Number mRNA:

  M33268.1

• Reactivity:

  Bovine

• Cross Reactivity:

  Bovine

• Sequence:

  AEDYAPYCKNQPGNCRIPLQSLFERATLVASNNYRLAREMFNEFNKQFGEGKNFTSKVINSCHTEFMTTPNNKEAAANTEDEALLRLVISLLHSWDEPLHQAVTELLHRNGASPDILARAKEIEDKTKVLLEGVEMIQKRVHPGEKKNEPYPVWSEKSSLTADDEDVRQTAFYRMFHCLHRDSSKISTYINLLKCRFTPC

• Assay Protocol:

  It is recommended to reconstitute the lyophilized bovine recombinant placental lactogen in sterile water or 0.4% NaHCO3 adjusted tp pH 8-9, not less than 100µg/ml, which can then be further diluted to other aqueous solutions, preferably in presence of carrier protein.

• Endotoxin:

  < 0.1 ng/µg of protein (< 1EU/µg)

• Purity:

  > 98.0% as determined by Gel filtration and SDS-PAGE gel.

• Bioactivity:

  Recombinant bovine recombinant placental lactogen is fully biologically active as evidenced by inducing proliferation of Nb2 cells.

• Length:

  199

• Form:

  Lyophilized

• Reconstitution:

  Water

• Molecular Weight:

  23.0 kDa

• Host or Source:

  E. coli

• N Terminal Sequence:

  AEDYAP