Kininogen

CAT: 0209-101-M537Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-101-M537Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Kininogen, also known as 2-thiol proteinase inhibitor, is a multi-functional protein. The high molecule weight (HMW) form of kininogen is synthesized as a precursor protein (amino acid residues 1 to 644) . The mature chain (residues 19 to 644) is further processed into the heavy chain (residues 19 to 380) and the light chain (residues 390 to 644) with release of the active peptide bradykinin. The heavy chain consists of three cystatin-like domains, which inhibit cysteine proteases. The light chain consists of a His-rich domain, which is associated with clotting activity.
Synonyms
KNG1; BDK; KNG
NCBI Gene ID
3827
UniProt
P01042
Accession Number
NP_001095886.1
Accession Number mRNA
NM_001102416.2
Chromosomal Location
3q27
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant Kininogen
Clone
(#11L36)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2

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