IP-10 (CXCL10)

• Description :

  Murine IP-10 is produced by several cell types during the delayed type hypersensitivity response. IP-10 acts as a chemoattractant towards monocytes, lymphocytes, and certain T cells. Recombinant Murine IP-10 is a 8.7 kDa protein, containing 77 amino acid residues.

• Synonyms :

  Cxcl10; C7; IP10; CRG-2; INP10; IP-10; Ifi10; mob-1; Scyb10; gIP-10

• NCBI Gene ID :

  15945

• UniProt :

  P17515

• Accession Number :

  NP_067249.1

• Accession Number mRNA :

  NM_021274.2

• Chromosomal Location :

  5 E2; 5 53.0 cM

• Reactivity :

  Mouse

• Cross Reactivity :

  Human, Mouse, Rat, Monkey

• Sequence :

  IPLARTVRCNCIHIDDGPVRMRAIGKLEIIPASLSCPRVEIIATMKKNDEQRCLNPESKTIKNLMKAFSQKRSKRAP

• Endotoxin :

  < 0.1 ng/µg of protein (< 1EU/µg)

• Purity :

  > 98% by SDS-PAGE & HPLC analyses

• Bioactivity :

  Assay #1: Determined by its ability to chemoattract IL-2 activated T cells using a concentration range of 0.1-10.0 ng/ml. Assay #2: Determined by its ability to chemoattract CXCR3 transfected/HEK293 cells using a concentration range of 100-500 ng/ml.

• Length :

  77

• Form :

  Lyophilized

• Molecular Weight :

  8.7 kDa

• Host or Source :

  E. coli