IL-7 Recombinant Protein

IL-7 Recombinant Protein

• Description: IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive. Recombinant human IL-7 is a 17.4 kDa protein containing 153 amino acid residues.
• Synonyms: IL7; IL-7
• CAS Number: 9000-83-3
• NCBI Gene ID: 3574
• UniProt: P13232
• Accession Number: NP_000871.1
• Accession Number mRNA: NM_000880
• Gene Location: 8q12-q13
• Host: E. coli
• Origin Species: Human
• Species Reactivity: Monkey, Mouse, Rat, Human, Leech
• Sequence: MDCDIEGKDG KQYESVLMVS IDQLLDSMKE IGSNCLNNEF NFFKRHICDA NKEGMFLFRA ARKLRQFLKM NSTGDFDLHL LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC FLKRLLQEIK TCWNKILMGT KEH
• Detection Range: The ED50 was determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 98% by SDS-PAGE & HPLC analyses
• Length: 153
• Form: Lyophilized
• Buffer: 10 mM Acetic Acid
• Molecular Weight: 17.4 kDa
• Shipping Conditions: Room Temperature