Mouse Anti-Human IL-1 alpha Monoclonal Antibody
CAT:
209-101-M776
Size:
100 µg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Mouse Anti-Human IL-1 alpha Monoclonal Antibody
- Description: IL-1α is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant human IL-1α is an 18.0 kDa protein containing 159 amino acid residues.
- Synonyms: IL1B; IL-1; IL1F2; IL1-BETA
- CAS Number: 9007-83-4
- NCBI Gene ID: 3553
- UniProt: P01583
- Accession Number: NP_000566.3
- Accession Number mRNA: NM_000575
- Gene Location: 2q14
- Host: Mouse
- Origin Species: Human
- Species Reactivity: Human
- Target Antigen: Human Recombinant IL-1alpha
- Isotype: IgG1
- Clone: (#7D35)
- Validated Applications: FC, N
- Purification Method: Protein G chromatography
- Form: Lyophilized
- Buffer: PBS
- Reconstitution: Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
- Shipping Conditions: Room Temperature
- Storage Conditions: Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.