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IGF-BP5

CAT: 0209-103-M238Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-103-M238Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IGFBP5 is expressed by fibroblasts, myoblasts and osteoblasts, making it the predominant IGFBP found in bone extracts. IGFBP5 has a strong affinity for hydroxyapatite, allowing it to bind to bone cells. When bound to extracelluar matrix, IGFBP5 is protected from proteolysis and potentiates IGF activity, but when it is soluble, IGFBP5 is cleaved to a biologically inactive 21 kDa fragment. Mouse, human and rat IGFBP5 share 97% identity.
Synonyms
Igfbp5; IGFBP-5; AI256729; AW208790; IGFBP-5P
NCBI Gene ID
16011
UniProt
Q07079
Accession Number
NP_034648.2
Accession Number mRNA
NM_010518.2
Chromosomal Location
1 C3; 1 36.1 cM
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Recombinant mouse protein of IGFBP-5
Clone
(#12C23)
Applications
WB
Purification Method
Protein G/A chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2

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