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IGF-BP3

CAT: 0209-103-M237Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-103-M237Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and several low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP) . All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF.
Synonyms
Igfbp3; IGFBP-3; IGgfbp3; AI649005
NCBI Gene ID
16009
UniProt
P47878
Accession Number
NP_032369.2
Accession Number mRNA
NM_008343.2
Chromosomal Location
11 A1; 11 1.35 cM
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Recombinant mouse protein of IGFBP-3
Clone
(#11B16)
Applications
WB
Purification Method
Protein G/A chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2

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