RegisterLogin

IGF-BP2

CAT: 209-100-198SSize: 5 µgDry Ice: NoHazardous: No
5 µgSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP2 is a cysteine-rich secreted protein produced by bone cells, and is most abundant in the brain. IGF-BP2 has been shown to inhibit IGF-II action in human breast and ovarian carcinoma cells. Recombinant human IGF-BP2 is a 31.5 kDa protein consisting of 289 amino acid residues including the IGF-BP domain and thyroglobulin type-I domain.
Synonyms
IGFBP2; IBP2; IGF-BP53
NCBI Gene ID
3485
UniProt
P18065
Accession Number
NP_000588.2
Accession Number mRNA
NM_000597
Chromosomal Location
2q33-q34
Reactivity
Human
Cross Reactivity
Mouse
Sequence
EVLFRCPPCT PERLAACGPP PVAPPAAVAA VAGGARMPCA ELVREPGCGC CSVCARLEGE ACQVYTPRCG QGLRCYPHPG SELPLQALVM GEGTCEKRRD AEYGASPEQV ADNGDDHSEG GLVENHVDST MNMLGGGGSA GRKPLKSGMK ELAVFREKVT EQHRQMGKGG KHHLGLEEPK KLRPPPARTP CQQELDQVLE RISTMRLPDE RGPLEHLYSL HIPNCDKHGL YNLKQCKMSL NGQRGECWCV NPNTGKLIQG APTIRGDPEC HLFYNEQQEA RGVHTQRMQ
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to inhibit IGF-I induced proliferation of FDC-P1 cells.
Length
289
Form
Lyophilized
Molecular Weight
31.5 kDa
Host or Source
Insect cells

Related Products

CatalogName
M60-118-L50IGF‑I / IGF-1 protein
600-163-L100IGF-2 / IGF-II Protein
M60-118-L1000IGF‑I / IGF-1 protein
600-163-L20IGF-2 / IGF-II Protein
M60-118-L20IGF‑I / IGF-1 protein
600-163-L1000IGF-2 / IGF-II Protein
100-203-L50IGF-BP7
100-203-L250IGF-BP7
M10-011-L100IGF-1
M10-011-L250IGF-1

Alternative Products

CatalogName
MBS692085-01Human IGF-BP2
MBS539394-01IGF BP2 protein
30R-AI105IGF BP2 protein
40-319-0005mgIGF-BP2 Recombinant Protein
40-319-01IGF-BP2 Recombinant Protein
7165-50IGF-BP2, human recombinant
40-319-002mgIGF-BP2 Recombinant Protein
7165-10IGF-BP2, human recombinant
PROTP18065Recombinant Human IGF-BP2 Protein
MBS8432288-01Human IGF-BP2 Recombinant Protein Lyophilized

Popular Products