Goat Anti-Rat IFN gamma Polyclonal Antibody

Goat Anti-Rat IFN gamma Polyclonal Antibody

• Description: IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ is species-specific and is biologically active only in human and primate cells. Recombinant rat IFN-γ is a 15.6 kDa protein containing 135 amino acid residues.
• Synonyms: Ifng; IFNG2
• NCBI Gene ID: 25712
• UniProt: P01581
• Accession Number: NP_620235.1
• Accession Number mRNA: NM_138880.2
• Gene Location: 7q22
• Host: Goat
• Origin Species: Rat
• Species Reactivity: Rat
• Target Antigen: Recombinant rat IFN-gamma
• Clone: Goat IgG
• Validated Applications: ELISA, WB, IHC (P)
• Purification Method: Antigen-affinity purified
• Form: Lyophilized from PBS
• Buffer: PBS
• Reconstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
• Shipping Conditions: Room Temperature
• Storage Conditions: The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.