Hedgehog interacting Protein (HIP)

• Description:

  Hedgehog-interacting protein) HIP) or Reg3B (regenerating islet-derived protein III beta; also PAPI) is a secreted, 17 kDa member of the Reg gene family, C-type lectin gene superfamily. It is found in pancreatic acinar cells, intestinal enterocytes and developing spinal motoneurons. Reg3B may play a role in intestinal epithelial cell renewal. It contains one C-type lectin domain. Mature mouse Reg3B is 91% and 67% aa identical to rat and human Reg3B, respectively.

• Synonyms:

  Hhip; hip; Xhip

• NCBI Gene ID:

  380097

• UniProt:

  Q7TN16

• Accession Number:

  NP_064655.4

• Accession Number mRNA:

  NM_020259.4

• Reactivity:

  Anti-Mouse

• Cross Reactivity:

  Mouse

• Target Antigen:

  Recombinant mouse protein of Hip EC-domain

• Clone:

  (#8L46)

• Applications:

  WB

• Purification Method:

  Protein G/A chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Rat

• Isotype:

  IgG2