GDF-3 Recombinant Protein
CAT:
209-100-179S
Size:
5 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No


GDF-3 Recombinant Protein
Description:
GDF-3 is a member of the TGF-β superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF-β family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia which characterizes Type 2 diabetes. Recombinant human GDF-3 is a 26.0 kDa non-disulfide-linked homodimer containing two 114 amino acid polypeptide chains.Synonyms:
GDF3; KFS3; MCOP7; MCOPCB6NCBI Gene ID:
9573UniProt:
Q9NR23Accession Number:
NP_065685.1Accession Number mRNA:
NM_020634Gene Location:
12p13.1Host:
E. coliOrigin Species:
HumanSpecies Reactivity:
MouseSequence:
AAIPVPKLSC KNLCHRHQLF INFRDLGWHK WIIAPKGFMA NYCHGECPFS LTISLNSSNY AFMQALMHAV DPEIPQAVCI PTKLSPISML YQDNNDNVIL RHYEDMVVDE CGCGDetection Range:
Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The ED50 for this effect is 100-150 ng/ml.Endotoxin:
< 0.1 ng/µg of protein (<1EU/µg)Purity:
> 98% by SDS-PAGE & HPLC analysesLength:
114Form:
LyophilizedMolecular Weight:
26 kDaShipping Conditions:
Room TemperatureCAS Number:
9000-83-3