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Galectin-1

CAT: 0209-400-015Size: 50 µgDry Ice: NoHazardous: No
CAT#:0209-400-015Size:50 µg
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with beta-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T-cells and T-leukemia cell lines and inhibits the protein phosphatase activity of CD45. Recombinant human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues.
Synonyms
Galectin-1; HBL; HPL; gal-1; HLBP14; galaptin; galectin 1; 14 kDa lectin; S-Lac lectin 1; lactose-binding lectin 1; 14 kDa laminin-binding protein; putative MAPK-activating protein PM12; beta-galactoside-binding lectin L-14-I; beta-galactoside-binding protein 14 kDa; GBP, GAL1; LGALS1
NCBI Gene ID
3956
UniProt
P09382
Accession Number
NP_002296.1
Accession Number mRNA
NM_002305.3
Chromosomal Location
22q13.1
Reactivity
Human
Cross Reactivity
Mouse, Human
Sequence
ACGLVASNLN LKPGECLRVR GEVAPDAKSF VLNLGKDSNN LCLHFNPRFN AHGDANTIVC NSKDGGAWGT EQREAVFPF QPGSVAEVCIT FDQANLTVKL PDGYEFKFPN RLNLEAINYM AADGDFKIKC VAFDLEHHHH HH
Assay Protocol
Centrifuge vial prior to opening. Human Galectin-1 should be reconstituted in water to a concentration of 0.1 mg/ml. This solution can be diluted in water or other buffer solutions or stored at -20°C.
Purity
> 95% by SDS-PAGE & visualized by Coomassie stain
Bioactivity
Testing in Progress.
Length
142
Form
Lyophilized
Buffer
PBS
Reconstitution
Water
Molecular Weight
14,5 kDa
Storage Conditions
The lyophilized human Galectin-1, though stable at room temperature, is best stored desiccated below 0°C. Reconstituted human Galectin-1 should be stored in working aliquots at -20°C.
Host or Source
E. coli
N Terminal Sequence
ACGLVASNLNLKPGE

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