Fractalkine (CX3CL1)

• Description:

  Fractalkine is a CX3CL chemokine that signals through the CX3CR1 receptor. Fractalkine has been shown to chemoattract monocytes, microglia cells and NK cells. Recombinant rat Fractalkine is an 8.7 kDa protein containing 76 amino acid residues, including the four conserved cysteine residues present in CC chemokines.

• Synonyms:

  CX3CL1; Cx3c; Scyd1

• NCBI Gene ID:

  89808

• UniProt:

  O55145

• Accession Number:

  NP_604450.1

• Accession Number mRNA:

  NM_134455.1

• Chromosomal Location:

  19p12

• Reactivity:

  Rat

• Cross Reactivity:

  Human, Rat

• Sequence:

  QHLGMTKCNI TCHKMTSPIP VTLLIHYQLN QESCGKRAII LETRQHRHFC ADPKEKWVQD AMKHLDHQTA ALTRNG

• Endotoxin:

  < 0.1 ng/µg of protein (< 1EU/µg)

• Purity:

  > 98% by SDS-PAGE & HPLC analyses

• Bioactivity:

  Determined by its ability to chemoattract human monocytes using a concentration range of 5.0-10.0 ng/ml.

• Length:

  76

• Form:

  Lyophilized

• Molecular Weight:

  8.7 kDa

• Host or Source:

  E. coli