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Fractalkine (CX3CL1)

CAT: 0209-100-173Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0209-100-173Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Fractalkine is a CX3CL chemokine that signals through the CX3CR1 receptor. Fractalkine has been shown to chemoattract monocytes, microglia cells and NK cells. Recombinant human Fractalkine is an 8.5 kDa protein containing 76 amino acid residues, including the four conserved cysteine residues present in CC chemokines.
Synonyms
CX3CL1; NTN; NTT; CXC3; CXC3C; SCYD1; ABCD-3; C3Xkine; fractalkine; neurotactin
NCBI Gene ID
6376
UniProt
P78423
Accession Number
NP_002987.1
Accession Number mRNA
NM_002996.3
Chromosomal Location
16q13
Reactivity
Human
Cross Reactivity
Monkey, Mouse, Rat, Human, Bacteria
Sequence
QHHGVTKCNI TCSKMTSKIP VALLIHYQQN QASCGKRAII LETRQHRLFC ADPKEQWVKD AMQHLDRQAA ALTRNG
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to chemoattract human T cells using a concentration range of 5.0-10.0 ng/ml.
Length
76
Form
Lyophilized
Molecular Weight
8.5 kDa
Host or Source
E. coli

UniProtKB · P78423

Fractalkine

X3CL1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P78423
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CX3CL1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
O00672
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

Cell adhesionChemotaxisHost-virus interactionInflammatory response

Cellular component

Cell membraneMembraneSecreted

Molecular function

Cytokine

PTM

Disulfide bondGlycoprotein

Domain

SignalTransmembraneTransmembrane helix

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Alternative Products

CatalogName
GT15024Fractalkine(CX3CL1)
MBS517008-01Fractalkine (CX3CL1)
HY-P71888-01Fractalkine/CX3CL1, Mouse
HY-P7180-01Fractalkine/CX3CL1, Human
MBS692067-01Human Fractalkine (CX3CL1)
43-578PCX3CL1 / fractalkine Peptide
E55A12445Human CX3CL1/Fractalkine
RC314-12Fractalkine, CX3CL1, human
RC354-12Fractalkine, CX3CL1, rat
EK0356h.Fractalkine/CX3CL1

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