Fractalkine (CX3CL1)

• Description:

  Fractalkine is a CX3CL chemokine that signals through the CX3CR1 receptor. Fractalkine has been shown to chemoattract monocytes, microglia cells and NK cells. Recombinant human Fractalkine is an 8.5 kDa protein containing 76 amino acid residues, including the four conserved cysteine residues present in CC chemokines.

• Synonyms:

  CX3CL1; NTN; NTT; CXC3; CXC3C; SCYD1; ABCD-3; C3Xkine; fractalkine; neurotactin

• NCBI Gene ID:

  6376

• UniProt:

  P78423

• Accession Number:

  NP_002987.1

• Accession Number mRNA:

  NM_002996.3

• Chromosomal Location:

  16q13

• Reactivity:

  Human

• Cross Reactivity:

  Monkey, Mouse, Rat, Human, Bacteria

• Sequence:

  QHHGVTKCNI TCSKMTSKIP VALLIHYQQN QASCGKRAII LETRQHRLFC ADPKEQWVKD AMQHLDRQAA ALTRNG

• Endotoxin:

  < 0.1 ng/µg of protein (< 1EU/µg)

• Purity:

  > 98% by SDS-PAGE & HPLC analyses

• Bioactivity:

  Determined by its ability to chemoattract human T cells using a concentration range of 5.0-10.0 ng/ml.

• Length:

  76

• Form:

  Lyophilized

• Molecular Weight:

  8.5 kDa

• Host or Source:

  E. coli