FGFR-3 (IIIb) S249C/Fc Chimera, soluble

• Synonyms:

  Fibroblast growth factor receptor 3, FGFR-3/ CD333

• NCBI Gene ID:

  2261

• UniProt:

  P22607-2

• Accession Number:

  NP_001156685.1

• Accession Number mRNA:

  NM_001163213.1

• Chromosomal Location:

  4q16.3

• Reactivity:

  Human

• Cross Reactivity:

  Human

• Label:

  Fc-Tag

• Sequence:

  ESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERCPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKSWISESVEADVRLRLANVSERDGGEYLCRATNFIGVAEKAFWLSVHGPRAAEEELVEADEAGSVYAGTRSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK

• Bioactivity:

  Measured by its binding ability to aFGF and FGF2 in a functional ELISA. In addition recombinant human soluble FGFR-3 (IIIb) S249C/Fc Chimera also binds to immobilized recombinant human FGF9 and FGF18.

• Length:

  585

• Form:

  Lyophilized

• Molecular Weight:

  65.0kDa

• Host or Source:

  Insect cells

• N Terminal Sequence:

  ESLGT