Products for Research Use Only
RegisterLogin

FAS

CAT: 0209-101-M707Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0209-101-M707Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Fas, also known as APO1, CD95, and TNFRSF6, was originally identified as a cellsurface protein which binds to monoclonal antibodies that were cytolytic for various human cell lines. In the new TNF Receptor superfamily nomenclature, Fas is referred to as TNFRSF6. Human Fas cDNA encodes a 325 amino acid (aa) residue type 1 membrane protein that belongs to the TNF and NGF receptor family. Alternatively spliced cDNAs encoding multiple Fas isoforms, including a soluble form of Fas lacking the transmembrane domain, have also been identified. Fas is highly expressed in epithelial cells, hepatocytes, activated mature lymphocytes, virus-transformed lymphocytes, and other tumor cells. Fas expression has also been detected in mouse thymus, liver, heart, lung, kidney and ovary. The ligand for Fas (FasL) has been identified and shown to be a member of the TNF family of type 2 membrane proteins. Fas-L is predominantly expressed by activated Tlymphocytes, NK cells, and in tissues with immuneprivileged sites. Soluble Fas-L can be produced by proteolysis of membrane-associated Fas.
Synonyms
FAS; APT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6
NCBI Gene ID
355
UniProt
P25445
Accession Number
NP_000441
Accession Number mRNA
NM_000043.4
Chromosomal Location
10q24.1
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human FAS
Clone
(#12J21)
Applications
Capture Ab
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

Alternative Products

CatalogName
CN-A038-500GMAgar, Micropropagation - Type I (Gracilaria)
M2302-20HPhaseShield™ Gel Tubes, Heavy (200x 2ml)
M2302-20LPhaseShield™ Gel Tubes, Light (200x 2ml)
BCS81BioCoupler® Glass Set (8 oz) x1
E-EL-H1579ELISA kit for Human PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9)
E-EL-M0380ELISA kit for Mouse CDKN1B (Cyclin Dependent Kinase Inhibitor 1B)
EA-IP-017MProtein L Magnetic beads
E-KAB-0415Human CA9 Antibody Pair Set
E-EL-M2699ELISA kit for Mouse ACTN1 (Actinin Alpha 1)
E-EL-H1851ELISA kit for Human DSG1 (Desmogleins 1)

Popular Products