Epiregulin

• Description:

  Epiregulin is a member of the EGF family of growth factors which includes, among others, Epidermal Growth Factor (EGF), Transforming Growth Factor (TGF) alpha, Amphiregulin (ARG), HB (heparin-binding), EGF, Betacellulin, and the various Heregulins. They are all synthesized as transmembrane precursors and converted to soluble forms by proteolytic cleavage. Epiregulin was originally purified from the mouse fibroblast-derived tumor cell line NIH3T3/T7 (1) .

• Synonyms:

  Proepiregulin, Epiregulin (EPR)

• NCBI Gene ID:

  13874

• UniProt:

  Q61521

• Accession Number:

  NP_031976.1

• Accession Number mRNA:

  NM_007950.2

• Reactivity:

  Anti-Mouse

• Target Antigen:

  Mouse recombinant protein Epiregulin

• Clone:

  (#6H12)

• Applications:

  E

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Rat

• Isotype:

  IgG2