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EGF (Animal Free)

CAT: 0209-M10-003-AFSize: 500 µgDry Ice: NoHazardous: No
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CAT#:0209-M10-003-AFSize:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-α and VGF (vaccinia virus growth factor) . Recombinant Murine EGF is a 6.0 kDa globular protein containing 53 amino acid residues, including 3 intramolecular disulfide bonds.
Synonyms
Epidermal growth factor; Egf; AI790464
NCBI Gene ID
13645
UniProt
P01132
Accession Number
NP_036974.1
Accession Number mRNA
NM_010113.3
Chromosomal Location
3 G3; 3 65.2 cM
Reactivity
Mouse
Cross Reactivity
Human, Mouse
Sequence
NSYPGCPSSY DGYCLNGGVC MHIESLDSYT CNCVIGYSGD RCQTRDLRWW ELR
Endotoxin
< 0.01 ng/µg of protein (< 0.1 EU/µg)
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses.
Bioactivity
The ED50 was determined by a cell proliferation assay using BALB/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
Length
53
Form
Lyophilized
Molecular Weight
6.0 kDa
Host or Source
E. coli

UniProtKB · P01132

Pro-epidermal growth factor

EGF_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
P01132
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Egf
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
EGF
EC number
—
Processing
Precursor
Secondary accessions
E9QNX6, Q569W5, Q6P9J2
Protein keywords

Technical term

3D-structureDirect protein sequencingReference proteome

PTM

Disulfide bondGlycoprotein

Domain

EGF-like domainRepeatSignalTransmembraneTransmembrane helix

Molecular function

Growth factor

Cellular component

Membrane

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