DNMT3A

CAT: 0209-101-M584Size: 50 µgDry Ice: NoHazardous: No
CAT#:0209-101-M584Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DNA (cytosine-5) -methyltransferase 3A is an enzyme that catalyzes the transfer of methyl groups to specific CpG structures in DNA, a process called DNA methylation. The enzyme is encoded in humans by the DNMT3A gene. This enzyme is responsible for de novo DNA methylation. Such function is to be distinguished from maintenance DNA methylation which ensures the fidelity of replication of inherited epigenetic patterns. DNMT3A forms part of the family of DNA methyltransferase enzymes, which consists of the protagonists DNMT1, DNMT3A and DNMT3B.
Synonyms
DNA (cytosine-5) -methyltransferase 3A, Dnmt3a, Cysteine methyltransferase DNMT3A, DNA methyltransferase HsaIIIA
NCBI Gene ID
1788
UniProt
Q9Y6K1
Accession Number
NP_001307821.1
Accession Number mRNA
NM_001320892.1
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human DNMT3A
Clone
(#14T9)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2

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