Cystatin C

• Description:

  Cystatin C is a member of family 2 of the cystatin superfamily. It inhibits many cysteine proteases such as papain and Cathepsins B, H, K, L and S. It is ubiquitous in human tissues and body fluids. A point mutation in the gene coding for the 120 amino acid mature Cystatin C causes a hereditary form of amyloid angiopathy in which the protein variant (Leu 68 to Gln) is deposited in the cerebral arteries, leading to fatal cerebral hemorrhage.

• Synonyms:

  Cst3; CysC

• NCBI Gene ID:

  13010

• UniProt:

  P21460

• Accession Number:

  NP_034106.2

• Accession Number mRNA:

  NM_009976.3

• Chromosomal Location:

  2 G3; 2 84.0 Cm

• Reactivity:

  Anti-Mouse

• Cross Reactivity:

  Mouse

• Target Antigen:

  Mouse recombinant Cystatin C

• Clone:

  (#4E59)

• Applications:

  WB

• Purification Method:

  Protein G/A chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Rat

• Isotype:

  IgG2