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CTGFL/WISP-2

CAT: 0209-100-147SSize: 5 µgDry Ice: NoHazardous: No
CAT#:0209-100-147SSize:5 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CTGFL/WISP-2 is a 28.6 kDa protein that belongs to the CCN family of cysteine rich regulatory proteins. Members of this family stimulate mitosis, adhesion, apoptosis, extracellular matrix production, growth arrest, and migration of multiple cell types. The protein is expressed in primary osteoblasts, fibroblasts, ovary, testes, and heart. In addition to promoting adhesion of osteoblasts, CTGFL/WISP-2 inhibits osteocalcin production, as well as binding of fibrinogen to integrin receptors. Recombinant human CTGFL/WISP-2 is a 24.8 kDa protein of 228 amino acid residues.
Synonyms
WISP2; CCN5; CT58; CTGF-L
NCBI Gene ID
8839
UniProt
O76076
Accession Number
NP_003872
Accession Number mRNA
NM_003881
Chromosomal Location
20q13.12
Reactivity
Human
Cross Reactivity
Human
Sequence
MQLCPTPCTC PWPPPRCPLG VPLVLDGCGC CRVCARRLGE PCDQLHVCDA SQGLVCQPGA GPGGRGALCL LAEDDSSCEV NGRLYREGET FQPHCSIRCR CEDGGFTCVP LCSEDVRLPS WDCPHPRRVE VLGKCCPEWV CGQGGGLGTQ PLPAQGPQFS GLVSSLPPGV PCPEWSTAWG PCSTTCGLGM ATRVSNQNRF CRLETQRRLC LSRPCPPSRG RSPQNSAF
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 95% by SDS-PAGE & HPLC analyses
Bioactivity
The ED50 was determined by its ability to inhibit IGF-II induced proliferation of MCF-7 is between 10-20 ng/ml in the presence of 15 ng/ml of human IGF-II.
Length
228
Form
Lyophilized
Molecular Weight
24.3 kDa
Host or Source
E. coli

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Alternative Products

CatalogName
MBS691756-01Human CTGFL/WISP-2
HC88838Human CTGFL/WISP 2
7129-10CTGFL/WISP-2, Human Recombinant
PROTO76076-1Recombinant Human CTGFL/WISP-2 Protein
TA328286Anti-Human CTGFL/WISP-2 Rabbit Polyclonal Antibody
TA328285Biotinylated Anti-Human CTGFL/WISP-2 Rabbit Polyclonal Antibody
MBS550728CTGFL
C7978-35BCTGFL (Connective Tissue Growth Factor-Like Protein, WISP-2, Wnt1-Inducible-Signaling Pathway Protein 2)
143304-01CTGFL/WISP-2, Recombinant, Human (Connective Tissue Growth Factor-Like protein, CCN5, CT-58)
MBS6470935-01CTGFL (Connective Tissue Growth Factor-Like Protein, WISP-2, Wnt1-Inducible-Signaling Pathway Protein 2) (HRP)

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