Clusterin

• Description :

  Clusterin (apolipoprotein J) is a 75-80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis. In humans, clusterin is encoded by the CLU gene on chromosome 8. CLU is a molecular chaperone responsible for aiding protein folding of secreted proteins, and its three isoforms have been differentially implicated in pro- or antiapoptotic processes. Through this function, CLU is involved in many diseases related to oxidative stress, including neurodegenerative diseases, cancers, inflammatory diseases, and aging

• Synonyms :

  Aging-associated gene 4 protein, Apolipoprotein J, Complement cytolysis inhibitor (CLI), Complement-associated protein SP-40, Ku70-binding protein 1

• NCBI Gene ID :

  1191

• UniProt :

  P10909

• Accession Number :

  NP_001822.3

• Accession Number mRNA :

  NM_001831.3

• Reactivity :

  Anti-Human

• Cross Reactivity :

  Human

• Target Antigen :

  Recombinant Human Clusterin

• Clone :

  (#11E38)

• Applications :

  E

• Purification Method :

  Protein G chromatography

• Assay Protocol :

  Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form :

  Lyophilized

• Buffer :

  PBS

• Reconstitution :

  PBS

• Storage Conditions :

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.

• Host or Source :

  Mouse

• Isotype :

  IgG1