Chemerin

• Description :

  Chemerin, also known as retinoic acid receptor responder protein 2 (RARRES2), tazarotene-induced gene 2 protein (TIG2), or RAR-responsive protein TIG2 is a protein that in humans is encoded by the RARRES2 gene. Chemerin is a chemoattractant protein that acts as a ligand for the G protein-coupled receptor CMKLR1 (also known as ChemR23) . Chemerin is a 14 kDa protein secreted in an inactive form as prochemerin and is activated through cleavage of the C-terminus by inflammatory and coagulation serine proteases. Chemerin was found to stimulate chemotaxis of dendritic cells and macrophages to the site of inflammation.

• Synonyms :

  Retinoic acid receptor responder protein 2, Rarres2

• NCBI Gene ID :

  71660

• UniProt :

  Q9DD06

• Accession Number :

  NP_001334097.1

• Accession Number mRNA :

  NM_001347168.1

• Reactivity :

  Anti-Mouse

• Target Antigen :

  Mouse recombinant Chemerin

• Clone :

  (#13G2)

• Applications :

  E

• Host or Source :

  Rat

• Isotype :

  IgG2