Chemerin

• Description :

  Chemerin is a secreted chemoattractant protein that can signal through the chemokine like receptor-1 (CMKLR1) . It is expressed in various tissues, including white adipose tissue, and circulates in blood as an inactive 143 amino acid precursor protein. Biologically active Chemerin is generated by proteolytic removal of C-terminal residues by several circulating proteases. Chemerin acts as a chemoattractant for cells expressing the CMKLR1 receptor, which includes certain dendritic cells, macrophages, and adipocytes. Recombinant human Chemerin is a 15.6 kDa protein consisting of 135 amino acid residues.

• Synonyms :

  RARRES2; TIG2; HP10434

• NCBI Gene ID :

  5919

• UniProt :

  Q99969

• Accession Number :

  NP_002880.1

• Accession Number mRNA :

  NM_002889.3

• Chromosomal Location :

  7q36.1

• Reactivity :

  Anti-Human

• Cross Reactivity :

  Human

• Target Antigen :

  Human recombinant Chemerin

• Clone :

  (#6G56)

• Applications :

  Capture Ab

• Purification Method :

  Protein G chromatography

• Assay Protocol :

  Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form :

  Lyophilized

• Buffer :

  PBS

• Reconstitution :

  PBS

• Storage Conditions :

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.

• Host or Source :

  Mouse

• Isotype :

  IgG2