Products for Research Use Only

Chem R23

CAT: 0209-101-M322Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0209-101-M322Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ChemR23, also known as Dez in mouse, is a seven-pass transmembrane, G-protein-associated receptor related to the chemoattractant C3a and C5a complement receptors. Although it shows less than 30% amino acid identity to the chemokine receptor family, it shows significant structural similarity. ChemR23 expression is limited to macrophages and dendritic cells. A ligand for ChemR23 has been identified as Chemerin, also known as Tig-2. Receptor-ligand binding elicits chemotaxis of macrophages and immature, but not mature, dendritic cells.
Synonyms
CMKLR1; DEZ; ChemR23; CHEMERINR
NCBI Gene ID
1240
UniProt
Q99788
Accession Number
NP_001135815.1
Accession Number mRNA
NM_001142343.1
Chromosomal Location
12q24.1
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant Chem R23
Clone
(#6A30)
Applications
FC
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS (sterile)
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2