Mouse Anti-Human CD105/Endoglin Monoclonal Antibody
CAT:
209-101-M160
Size:
100 µg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Mouse Anti-Human CD105/Endoglin Monoclonal Antibody
- Description: CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF-ß1 and ß3 with high affinity but not to TGF-ß2.
- Synonyms: Endoglin; END; ORW; HHT1; ORW1; CD105
- CAS Number: 9007-83-4
- NCBI Gene ID: 2022
- UniProt: P17813
- Accession Number: NP_000109
- Accession Number mRNA: NM_000118
- Gene Location: 9q33-q34.1
- Host: Mouse
- Origin Species: Human
- Species Reactivity: Human
- Target Antigen: Cell membrane glycoproteins of lymphoblastic leukemia Cells
- Isotype: IgG1
- Clone: (#12J11)
- Validated Applications: IHC
- Purification Method: Protein G/A chromatography
- Form: Lyophilized
- Buffer: PBS
- Reconstitution: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
- Shipping Conditions: Room Temperature
- Storage Conditions: Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.