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CD34, soluble

CAT: 0209-S01-069SSize: 5 µgDry Ice: NoHazardous: No
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CAT#:0209-S01-069SSize:5 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD34 is a highly glycosylated type I membrane protein that is selectively expressed on hematopoietic stem cells and vascular endothelium. It has been widely used as a molecular marker for the identification, isolation, and manipulation of hemopoietic stem cells and progenitors. CD34 can function as a regulator of hemopoietic cell adhesion by mediating the attachment of stem cells to bone marrow stromal cells or other bone marrow components. The full length human CD34 is a 385 amino acid protein, consisting of a 31 amino acid signal sequence, a 74 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain and a 259 amino acid extracellular domain. Recombinant human sCD34 is a 258 amino acid polypeptide containing only the extracellular domain of the full length CD34 protein which is fused to a C terminal His-tag (6xHis) .
Synonyms
CD34
NCBI Gene ID
947
UniProt
P28906
Accession Number
NP_001764.1
Accession Number mRNA
NM_001773.2
Chromosomal Location
1q32
Reactivity
Human
Cross Reactivity
Human
Label
His-Tag
Sequence
SLDNNGTATPELPTQGTFSNVSTNVSYQETTTPSTLGSTSLHPVSQHGNEATTNITETTVKFTSTSVITSVYGNTNSSVQSQTSVISTVFTTPANVSTPETTLKPSLSPGNVSDLSTTSTSLATSPTKPYTSSSPILSDIKAEIKCSGIREVKLTQGICLEQNKTSSCAEFKKDRGEGLARVLCGEEQADADAGAQVCSLLLAQSEVRPQCLLLVLANRTEISSKLQLMKKHQSDLKKLGILDFTEQDVASHQSYSQKTLEHHHHHH
Purity
> 95% by SDS-PAGE
Bioactivity
Data not available.
Length
267
Form
Lyophilized
Molecular Weight
28.6 kDa
Host or Source
E. coli
N Terminal Sequence
SLDNN

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