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CD16b

CAT: 0209-101-M293Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M293Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Receptors that recognize the Fc portion of IgG are divided into three groups designated Fc gamma RI, RII, and RIII, also known respectively as CD64, CD32, and CD16. In humans each group of receptors is encoded by 2 - 3 closely related genes designated A, B, and C. Fc gamma RI binds IgG with high affinity and functions during early immune responses. Fc gamma RII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses. Different Fc receptors can function as activators, as inhibitors, or as decoy receptors.
Synonyms
FCGR3B; CD16; FCG3; CD16b; FCGR3; FCR-10; FCRIII; FCRIIIb
NCBI Gene ID
2215
UniProt
O75015
Accession Number
NP_000561.3
Accession Number mRNA
NM_000570.4
Chromosomal Location
1q23
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human CD16b EC domain
Clone
(#5L11)
Applications
WB, FC
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2

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