CD3 epsilon

CAT: 0209-101-M303Size: 50 µgDry Ice: NoHazardous: No
CAT#:0209-101-M303Size:50 µg
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Description
The T cell receptor (TCR) /CD3 complex consists of two variable antigen-recognition receptor chains (TCR-alpha/TCR-beta or TCR-gamma/TCR-delta) that are non-covalently linked to at least four different invariant chains: CD3 gamma, CD3 delta, CD3 epsilon, and the CD3 zeta chain that exists as either a homodimer or as a heterodimer with its splice-variant the CD3 eta chain. The CD3 complex functions to transduce intracellular signals during TCR antigen recognition. CD3 is expressed early in thymocyte development, and on a subset of NK cells. CD3 epsilon is one of at least three invariant proteins that associate with the variable antigen recognition chains of the T cell receptor and function in signal transduction.
Synonyms
CD3E; T3E; TCRE
NCBI Gene ID
916
UniProt
P07766
Accession Number
NP_000724
Accession Number mRNA
NM_000733.3
Chromosomal Location
11q23
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human CD3 epsilon
Clone
(#3F43)
Applications
IHC, FC, Activation of T cells
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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