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CCRL-2

CAT: 0209-101-M286Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M286Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Chemokine receptors are seven-transmembrane domain G-protein coupled receptors that mediate the biological activities of chemokines. Most of these receptors exhibit promiscuous binding properties whereby several different chemokines signal through the same receptor. They are named according to the chemokine subfamily they bind. There are currently eleven CC-specific receptors designated CCR1 to CCR11. HCR (Human Chemokine Receptor), also known as CRAM, CKRX, and CCRL2, is a G protein-linked seven transmembrane domain spanning chemokine receptor that exists in two isoforms CRAM-A and CRAM-B. The two isoforms differ at the N-terminus with CRAM-A having an additional 12 amino acids. Cells reported to express HCR/CRAM include peripheral blood cells, monocytes, neutrophils, and T cells.
Synonyms
CCRL2; HCR; CKRX; CRAM; CRAM-A; CRAM-B
NCBI Gene ID
9034
UniProt
O00421
Accession Number
NP_003956.2
Accession Number mRNA
NM_003965.4
Chromosomal Location
3p21
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human CCRL-2
Clone
(#5A15)
Applications
FC
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2

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