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Carbonic Anhydrase IX

CAT: 0209-101-M153Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M153Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Carbonic anhydrase IX (CA9/CA IX) is an enzyme that in humans is encoded by the CA9 gene. It is one of the 14 carbonic anhydrase isoforms found in humans and is a transmembrane dimeric metalloenzyme with an extracellular active site that facilitates acid secretion in the gastrointestinal tract. CA IX is overexpressed in many types of cancer including clear cell renal cell carcinoma (RCC) as well as carcinomas of the cervix, breast and lung where it promotes tumor growth by enhancing tumor acidosis
Synonyms
Carbonate dehydratase IX, Carbonic anhydrase IX (CA-IX; CAIX), Membrane antigen MN, Renal cell carcinoma-associated antigen G250 (RCC-associated antigen G250)
NCBI Gene ID
768
UniProt
Q16790
Accession Number
NP_001207.2
Accession Number mRNA
NM_001216.2
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant Human Carbonic Anhydrase IX
Clone
(#3B15)
Applications
E, FC
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2

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