Artemin

CAT: 0209-102-P217Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-102-P217Size:100 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Artemin is a disulfide-linked homodimeric neurotrophic factor structurally related to GDNF, Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. Artemin, GDNF, Persephin and Neurturin all signal through a multicomponent receptor system, composed of RET (receptor tyrosine kinase) and one of the four GFRα (α1-α4) receptors. Artemin prefers the receptor GFRα3-RET, but will use other receptors as an alternative. Artemin supports the survival of all peripheral ganglia such as sympathetic, neural crest and placodally derived sensory neurons, and dompaminergic midbrain neurons. The functional human Artemin ligand is a disulfide-linked homodimer, of two 12.0 kDa polypeptide monomers. Each monomer contains seven conserved cysteine residues, one of which is used for interchain disulfide bridging and the others are involved in intramolecular ring formation known as the cysteine knot configuration. Recombinant human Artemin is a 24.2 kDa, disulfide-linked homodimer formed by two identical 113 amino acid subunits.
Synonyms
ARTN; EVN; NBN; ENOVIN
NCBI Gene ID
9048
UniProt
Q5T4W7
Accession Number
NM_001129687
Accession Number mRNA
NM_001136215
Chromosomal Location
1p33-p32
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Highly pure (>98%) recombinant hArtemin
Clone
Rabbit IgG
Applications
ELISA, WB
Purification Method
Antigen-affinity purified
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Form
Lyophilized from PBS
Buffer
PBS
Reconstitution
Water
Storage Conditions
The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
Host or Source
Rabbit

Alternative Products

CatalogName
GT15066Artemin
PT_39951-01Artemin Human Recombinant (Artemin Human)
545298Artemin (Biotin)
216143Artemin (ARTN)
OM297678-01Artemin Human
250550Artemin Antibody
AK9076-0005rHu Artemin
HC66603Human Artemin
HY-P7607-01Artemin, Human
30R-AA043Artemin protein

Popular Products