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ApoE3

CAT: 0209-102-P216Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-102-P216Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ApoE is a 34 kDa protein component of serum chylomicrons, VLDL, and HDL particles. It mediates the binding, uptake, and catabolism of these particles through interactions with the ApoE receptor and LDL receptors in the liver and brain. ApoE is important in fatty acid homeostasis and memory formation. Polymorphisms encode three variants (ApoE2, 3, 4) which are differentially related to the development of atherosclerosis and neurogenerative disorders. Mature human ApoE shares 71% amino acid sequence identity with mouse and rat ApoE.
Synonyms
APOE; AD2; LPG; LDLCQ5
NCBI Gene ID
348
UniProt
P02649
Accession Number
NP_000032.1
Accession Number mRNA
NM_000041.2
Chromosomal Location
19q13.2
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Highly pure (>98%) recombinant hApoE3
Clone
Rabbit IgG
Applications
ELISA, WB
Purification Method
Antigen-affinity purified
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Form
Lyophilized from PBS
Buffer
PBS
Reconstitution
Water
Storage Conditions
The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
Host or Source
Rabbit

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