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Angiostatin

CAT: 0209-101-M220Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M220Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Angiostatin, an internal fragment of plasminogen, is a potent inhibitor of angiogenesis, which selectively inhibits endothelial cell proliferation. Angiostatin potently inhibits tumor growth and can maintain metastatic and primary tumors in a dormant state. It is defined by a balance of proliferation and apoptosis of the tumor cells and is composed of plasminogen first four cringle structures. This molecule is generated by proteolytic cleavage of plasminogen.
Synonyms
Angiostatin
NCBI Gene ID
5340
UniProt
P00747
Accession Number
NP_000292.1
Accession Number mRNA
NM_000301.3
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human Kringle 1-3
Clone
(#6F34)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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