AMIGO2

• Description:

  Adhesion of cancer cells to vascular endothelial cells in target organs is an initial step in cancer metastasis. Previous studies revealed that Amphoterin-induced gene and open reading frame 2 (AMIGO2) promotes the adhesion of tumor cells to liver endothelial cells, followed by the formation of liver metastasis in a mouse model. However, the precise mechanism underlying AMIGO2-promoted the adhesion of tumor cells and liver endothelial cells remains unknown.

• Synonyms:

  Amphoterin-induced protein 2, Alivin-1, Differentially expressed in gastric adenocarcinomas (DEGA)

• NCBI Gene ID:

  347902

• UniProt:

  Q86SJ2

• Accession Number:

  NP_001137140.1

• Accession Number mRNA:

  NM_001143668.1

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Recombinant hu AMIGO2

• Clone:

  (#4D27)

• Applications:

  WB

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.

• Host or Source:

  Mouse

• Isotype:

  IgG2