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ALPL

CAT: 0209-101-M105Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M105Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue-nonspecific) . The first three are located together on chromosome 2, whereas the tissue-nonspecific form is located on chromosome 1. The product of this gene is a membrane-bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization. However, mice that lack a functional form of this enzyme show normal skeletal development.
Synonyms
Alkaline phosphatase, tissue-nonspecific isozyme, AP-TNAP; TNS-ALP, Phosphocreatine phosphatase
NCBI Gene ID
249
UniProt
P05186
Accession Number
NP_000469.3
Accession Number mRNA
NM_000478.5
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Native human ALPL
Clone
(#4C67)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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