AgRP

• Description:

  AgRP, also known as the protein product of the Agouti related transcript (ART), functions as an antagonist of the melanocortin (MC3 and MC4) receptors, both of which are implicated in obesity. AgRP levels are significantly elevated in the serum of obese mice and people.

• Synonyms:

  AGRP; ART; AGRT; ASIP2

• NCBI Gene ID:

  181

• UniProt:

  O00253

• Accession Number:

  NP_001129.1

• Accession Number mRNA:

  NM_001138.1

• Chromosomal Location:

  16q22

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Recombinant human AgRP

• Clone:

  (#32B12)

• Applications:

  WB, Capture Ab

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Mouse

• Isotype:

  IgG2