Adiponectin

CAT: 0209-102-P102Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-102-P102Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Adiponectin is an adipose-derived secreted protein containing 226 amino acid residues. It is relatively abundant in humans and rodents, accounting for about 0.01% of total plasma protein. The circulating levels of adiponectin are decreased under conditions of obesity, insulin resistance, and type II diabetes. Disruption of adiponectin in mice causes insulin resistance and neointimal formation. Conversely, administration of recombinant adiponectin suppresses hepatic glucose production, and reverses insulin resistance associated with both lipoatrophy and obesity. The protective role of adiponectin is attributed to its anti-inflammatory properties (e.g. ability to suppress expression of TNF-α and class A scavenger receptor in macrophages) .
Synonyms
Acrp-30, GBP-28, APM-1, Gelatin-binding protein, AdipoQ
NCBI Gene ID
9370
UniProt
Q15848
Accession Number
NP_001171271
Accession Number mRNA
NM_001177800
Chromosomal Location
3q27
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Hi-5 Insect cells derived Recombinant Human Adiponectin (#100-121)
Clone
Rabbit IgG
Applications
WB, ELISA
Purification Method
Antigen-affinity purified
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Bioactivity
WB: 0.1-0.2 μg/ml
Form
Lyophilized
Reconstitution
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Storage Conditions
The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
Host or Source
Rabbit
Isotype
Rabbit IgG

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